Spectrin-like proteins
نویسندگان
چکیده
منابع مشابه
Some properties of spectrin-like proteins from Pisum sativum.
Proteins cross-reacting with antibodies directed against alpha- and beta-spectrin were recently detected in plant cells. In this report we have studied the ability of these proteins to interact with other components of membrane skeleton such as ankyrin, f-actin and calmodulin. It was found that the polypeptide of high molecular weight reacting with anti-alpha-spectrin antibody binds calmodulin ...
متن کاملSpectrin and ankyrin like proteins in spermatids and spermatozoa of the hamster and some other mammals.
The presence of spectrin and ankyrin-like proteins was investigated during the differentiation and maturation of spermatozoa in mammalian species which have previously been studied for actin and calmodulin. These actin-binding proteins were characterized by immunoblotting and localized by immunoelectron microscopy. Neither spectrin nor ankyrin could be detected in the F-actin rich subacrosomal ...
متن کاملEndothelial cells express a spectrin-like cytoskeletal protein.
Vascular endothelium was investigated by indirect immunofluorescence and immunoautoradiography for the possible presence of spectrin-like molecules. Antibodies were raised against electrophoretically purified rat, rabbit, and bovine red blood cell spectrin and against rabbit brain fodrin. Antibody specificity was assessed by immunoblotting and double-diffusion technique. Homogenates of endothel...
متن کاملTowards a complete atomic structure of spectrin family proteins.
The spectrin family of proteins represents a discrete group of cytoskeletal proteins comprising principally alpha-actinin, spectrin, dystrophin, and homologues and isoforms. They all share three main structural and functional motifs, namely, the spectrin repeat, EF-hands, and a CH domain-containing actin-binding domain. These proteins are variously involved in organisation of the actin cytoskel...
متن کاملAsynchronous synthesis of erythrocyte membrane proteins ( erythropoiesis / spectrin / actin / glycoprotein )
The synthesis of membrane proteins of the mature mouse erythrocyte is asynchronous. During erythropoiesis, synthesis of the bulk of the spectrin and actin polypeptides is completed before that of the major transmembrane glycoprotein. Synthesis of the glycoprotein ceases before that of several minor proteins found on the inner surface of the red cell membrane, and one of these minor proteins is ...
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ژورنال
عنوان ژورنال: Nature
سال: 1976
ISSN: 0028-0836,1476-4687
DOI: 10.1038/260016a0